Current Studies

Current Studies

Clinical trials are vital in developing and evaluating new treatments for children with rheumatologic diseases. A list of our current studies can be found below.

TitleSponsor
A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of Obinutuzumab in Adolescents With Active Class III or IV Lupus Nephritis and the Safety and PK of Obinutuzumab in Pediatric Participants (POSTERITY)Hoffmann-La Roche
A Study to Evaluate the Drug Levels, Efficacy, and Safety of Deucravacitinib (BMS-986165) in Pediatric Participants With Juvenile Psoriatic ArthritisBristol-Myers Squibb
Non-IMP clinical study to generate data on the natural history of disease, biomarkers, and relevance of clinical endpoints in patients with selected type 1 interferonopathiesBoehringer Ingelheim
A Phase II Trial to Evaluate the Clinical Efficacy, Safety and Tolerability of MAS825 in Pediatric and Adult Participants With Still's DiseaseNovartis
A Phase 3, Multicenter, Open-label, Basket, Long-term Extension Study to Evaluate the Safety of Guselkumab in Pediatric Participants with Crohn’s Disease, Ulcerative Colitis or Juvenile Psoriatic ArthritisJanssen Research & Development, LLC
An open-label, multicenter study to evaluate pharmacokinetics, safety and tolerability of intravenous secukinumab infusions in pediatric subjects with Juvenile Psoriatic Arthritis.Novartis
Study of Oral Upadacitinib and Subcutaneous/​Intravenous Tocilizumab to Evaluate Change in Disease Activity, Adverse Events and How Drug Moves Through the Body of Pediatric and Adolescent Participants With Active Systemic Juvenile Idiopathic Arthritis. (SELECT-sJIA)AbbVie
A Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of Upadacitinib in Pediatric Subjects With Polyarticular Course Juvenile Idiopathic ArthritisAbbvie
An Efficacy and Safety Study of Intravenous Anifrolumab to Treat Systemic Lupus Erythematosus in Pediatric Participants (SLE)AstraZeneca
An Observational Registry of Abatacept in Patients With Juvenile Idiopathic ArthritisBristol-Myers Squibb
A Multi-Center, Open-Label Trial to Evaluate the Pharmacokinetics, Safety, and Pharmacodynamics of Subcutaneously Administered Belimumab, a Human Monoclonal Anti-BLyS Antibody, Plus Standard Therapy in Pediatric Participants with Systemic Lupus Erythematosus (SLE)GlaxoSmithKline